Knowledge creating capabilities and academic entrepreneurship

Knowledge management (KM) needs a systematic approach to develop capabilities that accelerate the evolution of knowledge as a key organizational resource. The purpose of this study was to investigate the impact of knowledge creating capabilities on academic entrepreneurial motivation in universities and mediating effect of self-esteem in this relationship. Motivational level of academic entrepreneurs is a strong predictor of commercialization initiatives and performance. The cultural and structural differences between universities and industry enforce to devise specific capability frame works to ensure successful completion of entrepreneurial activities. Data was collected from 8 universities in Pakistan. The purposive sampling was used to collect data from academic researchers and various statistical tools applied to the collected data. The results indicated that support of organizational structural, technological and cultural capabilities plays a remarkable role to boost up the academic entrepreneurs' self esteem

Clinical and etiological profile of Complicated Urinary Tract Infection in Children: A health facility-based cross-sectional study

Background: Urinary tract infection (UTI) is known to be the most frequent bacterial infection in the paediatric population. Objective: To determine the clinical profile and etiology of complicated urinary tract infection (UTI) in children. Methods: This cross-sectional study was done at the Department of Nephrology and Neonatology, National Institute of Child Health, Karachi from 1st January 2022 to 30th June 2022. In 241 children of either gender, (male and female) aged up to 15 years having structural or functional anomalies of the kidney and urinary tract or recurrent infection due to underlying kidney or urinary tract abnormalities were enrolled. Demographic and clinical characteristics along with laboratory parameters and etiological agents of complicated UTI were noted. Ultrasonography examination and dimercaptosuccinic acid (DMSA) renal scan (where indicated) were performed. Results: Of 241 children, 179 (74.3%) were male. The mean age was 3.08±3.63 years. Capillary refill time was prolonged in 78 (32.4%) children. Fever/chills, nausea/vomiting, urinary urgency, and dehydration were the most frequently noted clinical presentations reported in 232 (96.2%), 109 (45.2%), 91 (37.8%), and 89 (36.9%) children respectively. Ultrasonography findings were evident of bilateral moderative hydronephrosis in 60 (24.9%) children. E. coli followed by Pseudomonas and Klebsiella species were the most commonly found etiological agents noted in 98 (40.7%), 50 (20.7%), and 40 (16.6%) children respectively. Conclusion: The majority of the children with complicated UTIs were male. Fever/chills, nausea/vomiting, urinary urgency, and dehydration were the most frequently noted clinical presentations. The most commonly observed ultrasonography findings were bilateral moderative hydronephrosis

Ovarian Yolk Sac Tumor with Granulomatous Reaction Resembling Tuberculosis: A Unique Presentation

ABSTRACTYolk sac tumors (endodermal sinus tumors) are an important subgroup of germ cell tumors of the ovary. They are seen in young females andare highly aggressive, but respond well to treatment. Although different morphological patterns can be seen on light microscopy, granulomatousreaction and giant cells are a very rare occurrence. We report the case of a young female with ovarian yolk-sac tumor in which a widespreadgranulomatous reaction was seen, causing a diagnostic dilemma